Israelis prominent in selling counterfeit or illegal drugs online

November 23, 2009
Israelis and former Israelis are behind many of the world’s Internet sites that sell counterfeit or other illegal drugs online providing useless or dangerous products to people who think they are getting the real thing. With the help of the Israel Police, the Customs Authority and foreign units, caught numerous criminals says Mickey Arieli, director of the Health Ministry’s Pharmaceutical Crime Unit.

Arieli, a pharmacist who made aliya from Chicago nearly four decades ago and established the unit in 2007, said that prescription drugs meant to treat serious diseases like cancer, malaria or attention-deficit hyperactivity disorder but whose retail prices were unaffordable, were reaching the public, especially via illegal Internet sales. Yet Arieli and the two other professionals who constitute the unit told The Jerusalem Post in an interview that they were reaching only the "top of the iceberg" and that these activities seriously endangered public health.

"Our job is not to protect the intellectual property of legitimate pharmaceutical companies, but to protect public health," said Arieli, whose unit is located in two small rooms in the ministry’s national drug lab. In addition, erectile dysfunction drugs claiming to be Viagra and Cialis are widely marketed through illegal Internet sites and Hebrew newspaper ads, but are rarely the real thing. Rather, they are either harmless pills, or they contain drugs meant for other conditions.

Often, preparations claimed to be food supplements actually contain active pharmaceutical ingredients that could harm and even kill. He said that before the establishment of the Internet and the appearance of erectile dysfunction drugs, pharmaceutical crimes had been quite rare. Last year, a number of people died in Singapore from taking counterfeit food supplements that actually contained a drug meant for diabetics that brought down glucose levels. Elsewhere overseas, counterfeit drugs meant to treat malaria and/or cause abortion were actually made of paracetamol, which is a pain reliever and fever reducer and can be toxic to the liver if taken in high doses.

Fake or otherwise illegal "lifestyle" drugs such as erectile dysfunction drugs, diet pills and baldness treatments are the biggest sources of income for pharmaceutical criminals. Most counterfeit drugs, said Arieli, are manufactured in China, while generic "Viagra" is usually made in India and shipped to Israel. Illegal factories abroad and in Israel almost always function in very unsanitary conditions and not at the necessary temperatures and humidity.

Other global crimes include diversion, in which subsidized AIDS drugs meant to go to Africa, where the infectious disease is rampant, are shipped to Europe instead to be sold at higher prices. Counterfeit, illegal or dangerous medications often reach West Bank pharmacies. Arieli believes this rarely occurs in licensed Israeli pharmacies, but sometimes they do slip through, unintentionally or intentionally, via private pharmacists. Health fund pharmacies are the safest, he said,
because the funds purchase medications in bulk and supply their pharmacies nationally from a central source.

According to Arieli, illegal Web sites operated by Israelis or former Israeli residents usually have nothing to do with the manufacture of phony or illegal drugs, but expedite the transfer and payment for them. Besides the Internet, illegal medications such as amphetamines are sold at sex supply stores and in kiosks around the country, Arieli added. All of this is "black money."

He urges people to purchase medications, both over-the-counter and prescription drugs, only from pharmacies licensed by the Health Ministry. But Arieli stressed that people should also carefully look at medications they purchase, making sure that boxes and containers do not suddenly look different from what they have received before; that the printed warnings appear in Hebrew, Arabic and English rather than only in English or Arabic; and that the serial numbers and expiration dates on the packages are identical to those on the vials, dispensers or tubes inside.

Female Viagra for Sex Drive

November 17, 2009

The drug, flibanserin, had a disappointing effect on mood but did wonders for women’s flagging sex drive, researchers found.A drug which failed the test as an antidepressant could find a new use as the female "Viagra", scientists have said.Results from a series of clinical trials showed "significant improvements" in a number of measures of libido among women who had lost interest in sex.

Professor John Thorp, from the University of North Carolina at Chapel Hill, US, who led the research, said: "Flibanserin was a poor antidepressant. However, astute observers noted that it increased libido in laboratory animals and human subjects.

Women taking 100 milligrams of flibanserin once a day reported greater numbers of "satisfactory sexual encounters", higher levels of sexual desire, and reduced stress associated with sexual problems.

Viagra, which helps men overcome impotency, also began life with another purpose in mind. It was originally designed to treat angina, the chest pain associated with heart disease."It’s essentially a Viagra-like drug for women in that diminished desire or libido is the most common feminine sexual problem, like erectile dysfunction is in men."

Pooled results from three of four trials testing flibanserin’s ability to boost women’s sex drives were presented at the Congress of the European Society for Sexual Medicine in Lyon, France. A total of 1,946 pre-menopausal women aged 18 and older were treated either with flibanserin or an inactive "dummy" placebo drug for 24 weeks.

"Hypoactive sexual desire disorder" - or lack of sex drive - is believed to affect between 9% and 26% of women in the US. These results point to a novel approach to pharmacologic treatment of the sexual problem that plagues reproductive age women the most, and may over time prove to be an effective treatment without the side effects of androgen replacement therapy, which is the only treatment currently available," said Prof Thorp.

Treatment Options for Erectile Dysfunction

November 13, 2009
Erectile dysfunction is the inability of a man to achieve or maintain an erection sufficient for the needs of his partner.Most men experience this at some point in their lives, usually by age 40, and are not psychologically affected by it.Frequent erectile dysfunction can cause emotional and relationship problems, and often leads to diminished self-esteem.

Erectile dysfunction has many causes, both physical and psychological. Initial management for ED depends on the possible cause of the disorder in each individual patient. Men who experience erectile dysfunction have never had so many treatment options. Treatment options for ED have significantly improved over the past few years and new research and medications continue to increase treatment choices. Various therapies are available to successfully treat underlying physical causes and related emotional difficulties.

Treatment Options:

There are many treatment option for erectile dysfunction.Let them know one by one:

Oral Medications:

Oral medications used to treat erectile dysfunction include selective enzyme inhibitors (e.g., sildenafil [Viagra®], vardenafil [Levitra®], tadalafil [Cialis®]).The convenience of oral medications has made them the first-line ED treatment in many instances, yet studies indicate that between 30-70% of men do not respond to these drugs, and others experience many side effects including headaches, dizziness, blurred vision, and facial flushing. oral medications had become became one of the most well-recognized treatments for Erectile Dysfunction.

Viagra® is absorbed and processed rapidly by the body and is usually taken 30 minutes to 1 hour before intercourse. Results vary depending on the cause of erectile dysfunction, but studies have shown that Viagra is effective in 75% of cases. It helps men with erectile dysfunction associated with diabetes mellitus (57%), spinal cord injuries (83%), and radical prostatectomy (43%).

In clinical studies, Levitra® has been shown to work quickly, provide consistent results, and improve sexual function in most men the first time they take the drug. It also has shown to be effective in men of all ages, in patients with diabetes mellitus, and in men who have undergone radical prostatectomy.

Cialis® has been shown in clinical trials to stay in the body longer than the other selective enzyme inhibitors. It promotes erection within 30 minutes and enhances the ability to achieve erection for up to 36 hours.

Sex Therapy:

A significant number of men develop impotence from psychological causes that can be overcome. When a physiological cause is treated, subsequent self-esteem problems may continue to impair normal function and performance. Sex therapists emphasize the need for men and their partners to be motivated and willing to adapt to psychological and behavioral modifications, including those that result from medical or surgical treatment.

Penile Prosthesis:

Given the availability of less invasive, more effective treatments, penile prosthesis has become a treatment of last resort.  The best penile prosthesis is comprised of two inflatable tubes, a pump, and a reservoir. Pressing a valve on the pump mechanism deactivates it, and the fluid returns to the reservoir, resulting in a flaccid penis.Complications can include infection, bleeding, pain and discomfort, mechanical failure, or extrusion of part of the prosthesis through a weakened wall of the erectile chambers.

Penile Implants :

 
Penile implants involve surgical insertion of malleable or inflatable rods or tubes into the penis.  A semi-rigid prosthesis is a silicon-covered flexible metal rod.t requires the simplest surgical procedure of all the prostheses.n inflatable penile prosthesis consists of two soft silicone or bioflex (plastic) tubes inserted in the penis, a small reservoir implanted in the abdomen, and a small pump implanted in the scrotum. To produce an erection, a man pumps sterile liquid from the reservoir into the tubes by squeezing the pump in the scrotum.

 

Intra-Urethral Suppository:

MUSE contains a vasodilator known as Alprostadil prepared in the form of a pellet that is inserted into the urethra, via an applicator. While successful for some men, the effect is often limited given that it contains only one vasodilator which is poorly absorbed and rarely results in a complete erection on its own.  

Natural Treatment:

Nutritional and lifestyle choices that can contribute to difficulties achieving and maintaining an erection.It is important to consult a physician about erectile dysfunction to determine the cause, correct any underlying organic factor, and receive appropriate treatment.Poor dietary choices may lead to vascular disease (the most common cause of ED), which interferes with the erection process by restricting blood flow to the penis.Natural treatment can support erectile function by improving overall health.

Good nutrition may help improve erectile dysfunction.

  •   Eat whole, fresh, unrefined, and unprocessed foods. Include fruits (lots of richly pigmented berries to support vascular integrity), vegetables, whole grains, soy, nuts, olive oil, and cold-water fish (salmon, tuna, sardines, halibut, and mackerel).
  •    Avoid sugar, dairy products, refined foods, fried foods, junk foods, and caffeine.
 

Herbal Medicine :

Herbal medicines usually do not have significant side effects when used appropriately and at suggested doses. Occasionally, an herb at the prescribed dose causes stomach upset or a headache.It is recommended that only high-quality products be used.These herbs may be used to treat erectile dysfunction:

  • Damiana – Traditionally used as an aphrodisiac and for various sexual disorders; however, there are no current studies to confirm its effectiveness.
  • Asian ginseng – Traditionally used for male impotence, though no current studies support this usage.

Physical Medicine
  • Kegel exercises – Increase pelvic blood flow and muscle tone.
  • Exercise – Aerobic exercise and weight training support the cardiovascular system, increase overall energy, and promote relaxation while at rest.

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